Medical treatment of male infertility covers non-surgical therapies that target specific causes of reduced fertility, such as hormonal imbalance, infection or some ejaculation problems. The goal is to improve sperm production and quality, raising the chance of natural conception or supporting assisted reproduction.
Treatment starts with a careful diagnosis: semen analysis, hormone tests and examination, sometimes ultrasound and genetic testing. Depending on the cause, the doctor may prescribe gonadotropin injections for men with a deficiency, antibiotics for infection or medicines that regulate ejaculation, together with lifestyle advice.
No anaesthesia or hospital stay is needed, but patience and regular follow-up are, because sperm production takes roughly three months. Semen analysis is repeated at intervals to measure response and adjust the plan. The final result is usually clear after three to six months of consistent treatment, and longer in some hormonal conditions.
The final cost is set after a medical consultant reviews your case and photos.
Assoc. Prof. Dr. Zülfü Sertkaya is an Istanbul urologist who focuses on andrology. He graduated from Gazi University Faculty of Medicine in 2008, completed his urology residency at Haydarpaşa Numune Training and Research Hospital in 2014, and holds the FEBU title (2017). He worked at state, university and private hospitals, including Memorial Diyarbakır and Başakşehir Çam and Sakura City Hospital. Since 2022 he has run his own clinic in Zeytinburnu, focusing on penile prosthesis, Peyronie's disease, premature ejaculation and male infertility.
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It addresses the underlying cause rather than bypassing it, and in selected cases may restore natural fertility or improve ICSI outcomes.
Men with a cause that responds to medication, such as hypogonadotropic hypogonadism, genital tract infection, raised prolactin or retrograde ejaculation.
Bring previous test results and a list of your medicines. Never stop any medicine, such as blood thinners, on your own; the doctor decides. Avoid unsupervised testosterone, which can suppress sperm production.
As tablets or injections according to the doctor's plan, with follow-up visits and periodic tests to measure response.
It depends on the drug; hormonal injections may cause mild breast swelling or mood changes, which the doctor monitors and adjusts for.
No time off work is needed, but stopping smoking, managing weight, limiting alcohol and avoiding excess heat around the testes are advised.
Improvement usually starts after about three months; whether it lasts depends on the cause, as some conditions need only a course while others need longer follow-up.
Medication does not suit every cause and usually does not help obstruction or some genetic causes; no result can be guaranteed.
Depending on the diagnosis, IUI, ICSI, surgical sperm retrieval or surgery for a cause such as varicocele may be advised.
A short visit for diagnosis and planning is usually enough, with follow-up tests coordinated with the doctor, who decides when further visits are needed.
