How Long Does it Take for Nerves to Die After Radiofrequency Ablation?
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  • International Clinics
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  • 07 February 2025

How Long Does it Take for Nerves to Die After Radiofrequency Ablation?

Radiofrequency ablation (RFA) is a medical intervention that uses heat produced by radio waves to treat a wide range of conditions, such as chronic pain, spinal pain, tumors, varicose veins, and more.
It is a minimally invasive procedure that offers a good alternative option to various surgical treatments, including spine surgery—both open surgery and minimally invasive spine procedures like endoscopic spine surgery for treating back or neck pain.
Unlike cervical or lumbar spine surgery, which is considered more invasive and risky, radiofrequency ablation is a safe and effective approach that requires only a short recovery time before returning to normal life.
In this article, we will discuss the recovery period timeline in detail and explore how long it takes for a nerve to die after radiofrequency ablation.

Overview of Radiofrequency Ablation (RFA) Benefits and Uses

Benefits and uses of radiofrequency ablation:

1. Chronic pain relief:

Several painful conditions that do not respond to medical treatments such as severe pain in cervical and lumbar spine compression, can be effectively treated by radiofrequency ablation.

This includes neck and back pain, rheumatoid pain, and cancer produced pain.

2. In cancer:

Radiofrequency can reduce the size of some types of solid tumors

This facilitates the surgical removal of the tumor, minimizing the pain associated with its compression.

3. Varicose vein and other blood vessels

Radiofrequency ablation for varicose veins is an effective alternative option rather than surgical removal of the destructed vein and managing pain associated with poor blood supply to the legs.

4. Heart diseases:

Radiofrequency treats some cases of heart rhythm disorders such as atrial fibrillation.

How Does Radiofrequency Ablation Work?

In the radiofrequency ablation procedure, a small needle is inserted into the targeted area, guided by X-ray or ultrasound imaging to ensure accurate placement.

Then, a high-frequency electric current is passed into the affected area to generate high temperatures that destroy the targeted nerve or tissue causing pain.

RFA aims to provide long-lasting relief by interrupting the nerve's ability to send pain signals to the brain.

The effects can last from several months to over a year, but it does not cure the underlying condition.

How does radiofrequancy ablation work

Pros vs. Cons of Radiofrequency Ablation Technique

Advantaged of RFA:

1. A minimally invasive treatment approach that does not require incision formation or a prolonged recovery time, which is required in more invasive spine surgery.

2. Prolonged and effective management of chronic pain that does not respond to medications, improves the overall quality of life.

3. No downtime: Patients can return to normal life and even to work within a short period.

4. High precision.: By using advanced techniques to help the doctor apply the RFA accurately in the targeted site, this image-guided RFA effectively enhances the success rate and minimizes the risk of other tissue damage.

Disadvantages of RFA:

1. Not effective for all cases: unlike the more invasive surgery, in which the surgeon can observe, handle and treat the targeted area directly with a higher visible range.

Additionally, it is less effective in alleviating the pain in more complex cases or shrinking the tumor in several places.

2. Post-RFA side effects include swelling, bruising, and pain that result after heat generation and due to injection. However, these side effects occur temporarily and subside within a few days.

3. Risk of damage to other tissues: This is a rare complication; however, expert practitioners can make mistakes like wrongly inserting a needle. Another risk is damage to nearby tissue due to the generated high temperature.

4. The variability in the outcome's efficacy and durability due to condition complexity or in rare situations, nerve regeneration after radiofrequency ablation may occur, leading to pain to return to the patient unless another session is done

Radiofrequency Ablation Recovery Timeline: What Do Patients Expect?

What you should expect after having radiofrequency ablation therapy for treating painful diseases, such as radiofrequency ablation for lower back pain, is a variable sensation of side effects which may include severe pain, along with gradual improvement of your symptoms.

How to deal with the severe pain after radiofrequency ablation?

The RFA procedure, which involves damaging the nerve is painful by itself because the nerve will not die as soon rather it may be irritated at first and cause severe pain with a burning sensation, this condition may require a few days before the nerve dies and the overall pain subsides.

Your doctor will prescribe a painkiller to manage this pain until the RFA works and the nerve cell(s) die.

How long does it take for nerves to die and the radiofrequency ablation to work?

The nerve ablation by radiofrequency waves does not exert its effect on nerves immediately. rather it may require a period of 1 to 3 weeks to achieve its full effect and to relieve pain completely.

The overlap between the side effect and nerve death timeline may make the onset of action of such treatment slower than what you expect, however you will find improvement within 1 to 2 weeks and maximum.

How long is the recovery period after RFA?

The overall recovery period varies between patients and depends on the conditions complexity, the patient's overall health, and the RFA practitioner's experience.

  • Generally, the recovery period after RFA is short, as the procedure is minimally invasive and doesn't require general anesthesia like other major procedures.

  • During the first few days, you may experience some pain at the needle insertion site or a burning sensation and pain, that varies between mild and severe pain after RFA, in the site where heat was applied. However, this pain should not last more than a few days.

  • After this initial period, both the procedure-related pain and your original pain will start to subside, and your health will gradually return to normal.

  • Within 1 to 2 weeks, you can return to normal life and work activities. However, you should avoid heavy work or lifting during this stage.

  • Within 3 to 6 weeks, a complete recovery is typically observed. Any side effects or complications from the procedure will usually resolve completely. The treated nerve will typically be permanently altered, leading to long-term pain relief, and you can resume all normal activities.

  • Some severe, chronic, or complex cases may require 3 to 6 months to show improvement, especially when multiple nerves are involved or when tumors or malignant masses are the cause.

  • Patients should follow up with their doctors regularly to monitor treatment progress and determine if additional sessions are needed.

Related articles:

How Long Does it Take for Nerves to Heal After Back Surgery? A Complete Timeline

How Long Does it Take for Nerves to Die After Radiofrequency Ablation

Is the RFA Really Effective for Pain Management? How Long Does it Last?

The amount of pain relief varies by cause and location. However, most people experience significant relief after RFA, which typically lasts from six months to 12 months, and in some cases, even longer.

Radiofrequency Ablation (RFA) has been extensively studied for its role in managing various types of chronic pain, especially spine-related pain. Research highlights its efficacy and safety, offering a promising solution for patients who have not responded to other treatments.

A study published in Pain Medicine demonstrated that 87% of participants treated with RFA for chronic facet joint pain experienced a ≥60% reduction in pain at a 10-month follow-up (Oxford Academic).

Similarly, a review published on June 21, 2017, in Pain Medicine highlighted the frequent use of pulsed radiofrequency (PRF) for treating cervical and lumbar radicular pain, confirming its efficacy in these conditions. The authors concluded that PRF is a safe and effective option, particularly for patients with chronic radicular pain who have not benefited from other conservative approaches (NCBI).

This evidence reinforces the potential of RFA and PRF as reliable pain management solutions for spine-related conditions.

Does RFA Produce Permanent or Temporary Pain Management?

Radiofrequency ablation (RFA) typically produces permanent pain management for most patients, particularly when it comes to nerve damage in areas like the facet joints or for specific types of chronic pain.

However, the pain relief duration after RFA can vary depending on the condition being treated and individual factors.

Permanent in most cases: RFA causes permanent damage to the nerves responsible for transmitting pain signals, which leads to long-term or permanent pain relief in many cases, especially for chronic pain conditions such as facet joint pain or radicular pain.

Temporary in some cases: In rare situations, there can be partial recovery of nerve function, leading to a return of pain after a period of relief.

This is more common in complex conditions or if the technique doesn't target the nerve sufficiently.

Does Radiofrequency Ablation (RFA) Worth It? Patient Testimonials

A study analyzes patient perspectives on radiofrequency ablation (RFA) by reviewing discussions on Reddit.

It found mixed opinions: some users reported positive pain relief, with improvements lasting from 4 days to 36 months, while others experienced no benefits or adverse effects like worsening pain, arachnoiditis, and headaches.

The majority of patients felt that RFA was a worthwhile option, though there were concerns about expectations and insurance issues.

The results emphasize the importance of setting realistic expectations and managing potential risks.

To learn more about how radiofrequency ablation can be used for your condition, feel free to contact us at International Clinics and book a free consultation to find out if you are a candidate for this innovative technique.

References: clevelandclinic pmc academic  

FAQ's

Nerves can start to grow back after radiofrequency ablation (RFA) in about 6 to 12 months. However, the regrowth rate can vary depending on the type of nerve treated and individual factors. When nerves regenerate, the pain may return, but this typically takes several months or longer.

Pain after RFA is common due to temporary inflammation, nerve irritation, and the healing process. The pain may worsen before improving. If it persists or gets worse, consult your doctor to rule out complications.

After radiofrequency ablation (RFA), it typically takes 2 to 3 weeks for the nerve to fully "die" or lose its ability to transmit pain signals. The nerve tissue is damaged by heat during the procedure, and although the nerve doesn't instantly stop working, it gradually loses function over time. Full pain relief may take a few weeks to be fully noticeable.

Side effects of burning nerves in your back can include temporary pain, nerve injury (like numbness or tingling), infection, muscle weakness or spasms, and the return of pain as nerves regrow. These are rare, and most people experience relief with minimal issues.