What is the Best Injection for Weight Loss?
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What is the Best Injection for Weight Loss?

Obesity is one of the major health related problems around the world. Obesity and overweight are serious health issues that increase the risk for premature death and a variety of health problems, including heart attack and stroke.

According to a comprehensive global study conducted by Imperial College London and published in The Lancet. More than one in ten men and one in seven women across the globe are now obese, according to the worlds biggest obesity study.

In contrast to weight gaining, losing weight is not as fast as required. Almost all methods recommended for weight loss need weeks to months to show significant results, weeks of hard training and a lot of food deprivation.

Recently, there has been a revolution in the field of medicine with new injectable drugs, which have become widely adopted as a novel solution for managing obesity in several major countries, including the US, UK, and Australia.

What is the Best Injection Drug for Weight Loss?

When considering the best injection drug for weight loss, medications like Saxenda (liraglutide), Wegovy (semaglutide), and Mounjaro (Tirzepatide) stand out. These FDA-approved drugs are specifically designed to help patients manage obesity by targeting hormones that regulate appetite and glucose metabolism.

Surgical options for obesity can be achieved through Gastric Sleeve surgery. Know every thing about gastric sleeve in:

How safe is Gastric Sleeve and increase your knowledge through Gasrtic sleeve before and after skin changes.

Injection for Weight Loss

How Do These Injections Work for Weight Losing?

When we eat food, our gut releases hormones that help the body regulate hunger and blood sugar levels. One of these hormones is called GLP-1 (glucagon-like peptide-1).

GLP-1 improves insulin function to lower blood sugar levels and delay gastric emptying, decreasing appetite.

GLP-1 also communicates with the brain’s appetite control centre, the hypothalamus, to lower food-seeking behaviour.

The injectable drugs work through hormones that regulate appetite, hunger, and glucose metabolism.

Unlike traditional oral weight loss pills, injectables have a more direct approach to managing hunger and food intake, often leading to more significant weight loss results.

Another option for slimming body in overweight patients is liposuction. Read about How liposuction is done

Discover Vaser and Laser liposuction techniques

Also know How much fat can liposuction remove

Who are Best Candidates for Obesity Treatment by the Injectable Wegovy, Saxenda and Mounjaro?

FDA approved medications for using as injections for treating:

  • Obese with BMI 30 or over or Overweight patients with BMI 27 but associated with other comorbidities such as heart disease, hypertension, high blood cholesterol level or diabetes mellitus.

  • For reducing the risk for heart disease in overweight patients with medical history for heart disease

  • People who did not benefits from dietary changes and exercise

  • Used along with diet and exercise to help improve blood sugar (glucose) in adults with type 2 Diabetes Mellitus.

Who Can not Benefit from Injectable Treatments for Obesity?

  • Pregnant or breastfeeding women

  • Patients with thyroid cancer or having history for throid cancer

  • Have multiple neoplasia syndrom type 2

What is the Best Injection for Weight Loss and Diabetes?

One of the most significant effects of the injectable drugs for weight loss is their blood sugar controlling effect and insulin synthesis enhancement. This is specially with Mounjaro that exert its effect through two hormones GLP-1 and GIP. This makes it the ideal solution for patients suffering both obesity and diabetes mellitus.

The Best Injection for Weight Loss at Home

The good news about these weight loss injections is that they are safe and applicable. They can be used easily and safely at home. They do not need any close supervision unless persistent side effects occur.

All of the three injectable drugs can be used safely at home.

However, to achieve the best weight loss injection use without harmful effect, you should follow the doctors instructions carefully and to minimize mistakes, keep them away from any person.

What is the best injection for weight loss in 2024?

Mounjaro ,with the active ingredient is Terzipatide that has got the FDA approval for weight loss only in 2023 is the best injection used for weight loss in 2024

As mentioned in the Second Nature Journey:

“Based on data from randomised controlled trials , the best weight-loss injection that’s available in the UK in 2024 is called tirzepatide, sold under the brand name Mounjaro in the UK”.

These injections were discovered originally for treating people suffering from type 2 Diabetes Mellitus. However inِ Aug 2023 FDA approved its use for chronic weight management in adults with obesity and overweight.

Weight Loss Injection

What is the Best Injection for Weight Loss in the US?

Wegovy and Saxenda are widely available in the United States. Additionally, Mounjaro is currently available and all three medication are approved by the FDA

What is the Best Injection for Weight Loss in the UK?

In the UK, both Saxenda and Wegovy are among the best injections that are widely used for weight loss, they are available through clinics and pharmacies.They are available in the UK after approval by the European Medicines Agency (EMA).

Recently, Mounjaro was approved by EMA for treating obesity and overweight.

What is the best injection for weight loss in Australia?

In Australia Saxenda injections has been approved by the Therapeutic Goods Administration (TGA) since 2018. They have gained popularity due to their proven effectiveness in managing obesity.

Also Wegavy approved by the TGA in 2022 for treating obesity in Australia

Mounjaro It is also available in Australia but its approval currently is for the treatment of type 2 diabetes and is expected to be approved laterly for obesity.

Can Injection for Weight Loss Cause Side Effects?

Some minor to moderate side effects can occur when starting using these injections such as nausea, low blood sugar, constipation or diarrhea. Your body will overcome these side effects over time. However, if you feel these side effects are un tolerable you should call your doctor immediately.

Are the Injections Used for Weight Loss Safe for Children?

Both semaglutide (Wegovy) and Liraglutide (Saxenda) are safe and FDA approves for children aged 12 and older when prescribed by a healthcare provider, whereas Tirzepatide is not yet approved for use in children.

Dive Deeper:

A Comprehensive Comparison of Saxenda, Wegovy, and Mounjaro for Weight Loss

Wegovy

Saxenda

Mounjaro

Active ingredient

Semaglutide

Liraglutide

Tirzepatide

When do the effects appear?

People usually begin to notice appetite suppression and weight loss within the first 4 weeks, with significant results typically visible after 12 to 16 weeks of consistent use.

the effects may start to show within 4 to 6 weeks, with more significant results visible around 12 weeks.

Users can generally see the first signs of effect within 4 to 6 weeks, with more noticeable results after about 12 weeks.

Drug effectiveness:

Weight loss amount

Clinical studies show that users of Wegovy can lose 15% to 20% of their body weight after 1 year.

Liraglutide can lead to a 5% to 10% weight loss over the course of a year.

Studies suggest tirzepatide can result in 15% to 22% body weight loss within 12 months, potentially offering better results than semaglutide.

How it works

Memic GLP-1 Hormone

Memic GLP-1 Hormone

Memic two hormones GLP-1 and GIP

How to use

Once weekly

Once daily

Once weekly

approval in countries

In the US, UK, and Australia

In the US, UK and Australia

In the US only

Main approved indication

used for obese patients who have other comorbidity disease

Used for obese/overweight patients adult and children above 12 years

Used for DM and can be used for obesity

pros of the injection used for weight loss

Effective for general weight loss

Once weekly so less pain and more compliance

A more affordable option

The most effective one as it work on two hormons

Once weekly so less pain and more compliance

cons of the injection used for weight loss

Expenisve

Need several weeks to show results.

Daily injection

less weight loss effectiveness compared to the others.

Expensive

approved only in the US

FAQ's

Mounjaro, exerts its effect through dual hormonal memetic effect, several studies approve its efficacy that can reach up to decreasing 22% of the total body weight.

According to several trials, Wegovy has exerted a more significant weight lowering effect with efficacy that can reach up to 20% decrease in body weight

Without keeping a regular healthy lifestyle including healthy food and exercises there is no method that can guarantee permanent effect. Weight loss injections are not permanent; it reduces your appetite as long as you use them.

As long as weight loss injections are prescribed by doctor and are used carefully following instructions, they are safe